Outpatient Treatments for COVID-19 Reviewed

Dr. Pierre Kory is one of the leaders in the movement to provide early care for COVID infection. Kory is a critical care physician( ICU specialist ), triple committee attested in internal medicine, critical care and pulmonary medicine, and is part of the Frontline COVID-1 9 Critical Care Alliance( FLCCC ), which was among the first to publish COVID treatment guidance.

Kory spent most of his busines at the Beth Israel Medical Center in Manhattan, New York, where he cured extended the intensive care unit. He also had a busy outpatient practice. About six years ago, he was recruited to the University of Wisconsin Medical Center in Milwaukee, Wisconsin, where he preceded the critical care service. “When COVID affected, I was in a lead rank, ” he says. “I resigned, because of the highway they were handling the pandemic.”

Treatment Option Have Been Vehemently Opposed

University of Wisconsin Medical Center, like most infirmaries across the U.S ., insisted on providing supportive care only, and Kory refused to remain in a leader post under those circumstances. Patients were, for the first time in modern medical record, told to merely suffer at home until they were near extinction, then go to the hospital where they were placed on deadly ventilator treatment.

“I knew there was a variety of therapies that we could use[ more] we were using nothing, ” he says. Doctors were even told to not use anticoagulants, even though blood clotting was “through the roof” in numerous cases. “You could draw blood and actually hear the blood clotting very quickly in the tubes, ” he says.

Since those early days, the disease seems to have changed considerably. We don’t envision the high rates of blood clotting anymore, for example, which is good news.

But for some reason, from the very start, “they were literally telling us that we needed randomized restrained tests to do anything, ” Kory says, and to this day, health authorities are refusing to acknowledge any medication etiquette outside of the incredibly hazardous experimental stimulant remdesivir, and the experimental COVID jabs.

“People were dying,[ yet] all of my suggestions were get roared down. My directors were showing up[ to my clinical engagements] and get me to stand down, because I was entertaining the idea that we should do this, that and the other thing, and they didn’t want anything to be done.

And so, I said,’ I’m done.’ I resigned mid-April 2020. I then went to New York for five weeks and ran my old-fashioned ICU in New York.”

The Importance of Steroids in the Treatment of COVID-1 9

In May 2020, Kory certified before the U.S. Senate, emphasizing how critical it was to use steroids during the hospital phase of this infection. At that time, he was still employed by the University of Wisconsin. His resignation date had not yet happened, and they “were indignant that I was speaking in public, uttering my opinion.”

This is remarkable, because when you’re an expert in a field, “you’re actually responsible to share your insight and expertise, ” Kory says. “Yet they were very unhappy that I was doing that.”

Seven days later, Kory was absolved when the British Recovery trial develops came out, presenting the benefits of corticosteroids. Since then, steroids have become part of standard of care in the hospital phase.

Steroids are an effective tool for reducing inflammation in general, but they emerge especially important for advanced COVID infection. I had a close friend who contracted a very serious case of COVID-1 9 and hindered degenerating despite making everything I advocated.

He knew Dr. Peter McCullough, so he texted him and was told to add prednisone and aspirin to his current regimen. As soon as “hes taking” the prednisone, he started to do better.

As explained by Kory, this is a common event. Importantly, the evidence shows that when squandered early, during slight infection, corticosteroids do more harm than good. But once you are entering into moderate illness, as soon as you start to see lung dysfunction or the need for oxygen, steroids are critical and are clearly lifesaving.

Steroids Must Be Used at the Correct Time

One of the reasons for this is because SARS-CoV-2 illnes provokes a very complex cascade of inflaming. More specifically, Kory says, severe COVID-1 9 is a macrophage activation syndrome. It’s the hyperinflammatory macrophages( a subtype of macrophages) that end up causing organ detriment. So, you want to use medicines that either suppress specific activities or repolarize them into hypoinflammatory macrophages.

The key is to use the steroids at the correct time — not too early and not too late, the “Goldilocks” window. There are no hard and fast rules for that, as each patient is different, but as a rule of thumb, do NOT use it until or unless you are seeing a significant worsening of evidences to where breathing is getting more difficult.

Kory’s outpatient protocol includes prednisone on Day 7, 8 or 9, if you’re still going downhill. It is important to NOT use it early in the course of the illness as it will actually worsen the infection by increasing viral replication.

The proposed dosage is 1 milligram of prednisone or methylprednisolone per kilogram of bodyweight. When using methylprednisolone( Medrol)( which Kory favors, in part because lung tissue concentrations are higher than prednisone ), he fractions it into two daily doses. Kory does not recommend the use of dexamethasone, as it doesn’t work as well for lung malady. Yet, most physicians in the U.S. application dexamethasone if they’re employing steroids at all.

The dose may be increased depending on the severity and trajectory of the illnes. “I probably will either double or triple the[ dosage] until I can get them stable, ” he says.

“Once they’re off oxygen, then I taper off[ the steroid] over about a week to 10 dates, sometimes shorter. Depends how long they were on oxygen. If they were on it for a short period of time, I do a fast diminish; if they were on oxygen for a longer time, I’ll do a slower diminish. But I don’t start amply decreasing until they’re off oxygen.”

Anticoagulants — When to Use Them

As mentioned earlier, while early COVID-1 9 cases often involved severe blood clotting, that aspect of the illnes appears to have waned. Even when clotting occurs, it’s typically much milder than which is something we ascertained in the initial stages. Still, anticoagulants can be an important component in these cases.

“What I do with coagulation is, I generally follow the D dimer on admission. D dimer is a marker of endothelial injury and clotting. In patients with regular D dimers, I’ll only do routine prophylaxis quantities. If it’s moderately promoted, I do moderate[ quantities] and if it’s dangerously hoisted, I’ll do full quantity anticoagulants, ” Kory explains.

He normally expends an anticoagulant called Lovenox. Cases are also uttered full-dose aspirin, unless there’s a contraindication. I suppose fibrolytic enzymes like lumbrokinase and nattokinase, which promotion cheapened fibrin, may be a better alternative to aspirin. N-acetyl cysteine( NAC) is another potential candidate. Kory is not convinced, however πŸ˜› TAGEND

“We have exploited NAC in different disease modelings over the years. It’s a standard treatment for acetaminophen overdose, but not for pulmonary fibrosis. In pulmonary medicine, of which I’m an expert, we had decades which is something we studied NAC for that. None of those studies washed out. In sepsis, it didn’t truly pan out.

And so, for severe disease, we think it’s an effective drug and it’s a good antioxidant. I think it does have anticoagulation[ influences ], but our opinion is that it’s generally strong. So, for the hospital phase, we think it’s too weak.”

Vitamin C

Another important component is intravenous vitamin C. While some university hospitals may carry IV vitamin C, most don’t but might be able to get it from another neighbourhood infirmary. Importantly, the vitamin C needs to be administered within the first six hours of admittance to the ICU in order to work, and it may be similar for COVID.

This is especially true for the relatively low doses recommended by the Math+ etiquette of 1,500 mg or 1.5 grams. Many outpatient natural medicine specialists will be implemented by 25 grams to 50 grams of IV vitamin C, but most hospices is not allow this high a dose, even though it is likely that higher doses will work if you missed the early medicine window( the first six hours ). So pragmatic logistics is why the Math+ protocol use relatively low doses.

One suggestion would be to call the hospital you’re thinking of using if you ever had to be admitted for COVID and ask if they have it. If not, you can ask your doctor to fiat it for you and fetching it to the hospital, if you or a family member are admitted for COVID or sepsis. The key, of course, is having a doctor who is willing to use it. Some aren’t.

“You should’ve seen the fighting I get. At one point, I was the director of the main ICU at the University of Wisconsin and the data was so overwhelming, I said,’ Hey, guys, can’t we just start a etiquette where we just cause everybody on admittance IV vitamin C? What’s the downside? ’

Everyone started talking about kidney stones and all of this nonsense, and we have so much data are demonstrating that doesn’t happen in acute illness, or in IV formulations … I feel like I live in a cartoon of drug, because each time I to have a few words with someone, they just don’t repute anything pieces. Because if it made, they would be doing it. It’s bizarre.”

The FLCC Protocol

Sadly, the purposeful stupidity of many physicians is literally killing many COVID patients who could have, and “shouldve been”, been saved. There’s exactly no doubt that protocols such as the one developed by the FLCC and the other groups listed below could have saved numerous, had it been widely implemented. Yet despite its success, many hospices to this day do not use it.

“Our protocol is always evolving, ” he observes. “We’re not saying that this is the only way to treat it. This is how we decided to treat it. We reserve the right to deprioritize or deepen the dose, or replace a brand-new medicine.

We want to follow the data, the experience and the knowledge of this infection. That’s No. 1. No. 2, all of our etiquettes are combining rehabilitation protocols.

And by the way, that makes doctors fits. You know why? Because they want to know, how do you know that this is necessary? The report contains experiments of each individual component showing that they’re effective. We believe they’re synergistic, but we’re never going to see do a visitation to test every component on our protocols.

But there are a number of other etiquettes. The AAPS has a protocol. 1 The World Council for Health, 2 they have a number of options. So there are many doctors who might emphasize or de-emphasize a drug on our protocol. And we is not impersonate that ours is the only highway. But we do thrown a good deal of judge into it.

Most of our remedies are repurposed, so they’re not story. They’re very well-known over decades, their security sketches is known, they tend to be generally low cost, and their mechanisms are well-known. A central remedy to all of our protocols — avoidance, early management, hospital, and late time like long-haul[ illnes] is ivermectin, for numerous reasons.”

Why Ivermectin?

As noted by Kory, ivermectin is a potent antiviral. “That’s been demonstrated for 10 years now in the laboratories on a number of viruses, ” he says. “They’ve shown that it interrupts replication of Zika, Dengue, West Nile, even HIV. And then the clinical studies are just overwhelming.” He continues πŸ˜› TAGEND

“Can I just take one minute to say that if anyone wants to call ivermectin a controversial remedy, I really want to call out it is absolutely not controversial.

It is a medicine that is buried in corruption, and the dishonesty is in the suppressing of its efficacy. There are immense capabilities that do not want its efficiency and effectiveness of that drug to be known because, if it is known and becomes standard of care, it will obliterate the market for a number of novel pharmaceutical products.

When you look at the actions taken against ivermectin, it can only be understood that it’s threatening something big and powerful, because boy has it been attacked[ even though it’s been used in] 64 ensure visitations, almost every single one of them presenting welfare, many of them massive benefits.

Yet they contort it to make it seem like it’s controversial. It’s absurd. We are well aware offices. We are well aware from in vitro, in vivo animal studies, and instance series.”

One of the first case series, from the Dominican Republic, was issued in june 2020. They plowed 3,300 consecutive emergency room COVID cases with ivermectin. Of those, only 16 went on to be hospitalized and one died. That’s somewhat profound, considering these were severely ill individuals.

Importantly though, there is a dose-response relationship to the viral consignment. The Delta variant has been shown to produce viral consignments that are 250 times higher than Alpha, and as Delta became predominant, breakthrough cases in the avoidance etiquette started happening.

“I’m one of them. I went COVID while I was taking it weekly, ” Kory says. “Now we’re make it twice weekly. Is it the claim dose? We’re not sure. But we’re seeing much fewer breakthroughs now on a higher dose. Could it be higher? Maybe. But, but we know it tasks as prevention.”

Higher dosages of ivermectin are also used for treatment of Delta. In more advanced theatres, the drug is useful thanks to its anti-inflammatory assets. Contrary to many other medications, ivermectin is beneficial in all stages of the infection.

Vitamin D Optimization Is Crucial

Other components of the FLCC’s prevention and treatment etiquettes include concoctions that have either antiviral or anti-inflammatory belongings, or a combination thereof, such as melatonin, quercetin and zinc, and anticoagulants such as aspirin.

If you haven’t done so previously, check your vitamin D blood level and if it’s below 40 ng/ mL, start taking an oral complement. Don’t wait until you’re sick.

Ideally, everyone would optimize their vitamin D height before ever needing medicine for COVID. If you haven’t done so once, check your vitamin D blood level and if it’s below 40 ng/ mL, start taking an oral supplement. Don’t wait until you’re sick. The medical literature proposes population-wide vitamin D optimization, to a height above 40 ng/ mL, could have reduced COVID morbidity and death by about 80%.

“No question, ” Kory says. “In fact … there was a study that came out, a huge database of patients, where they looked at the individuals who tested their vitamin D tiers before they got ill. They reckoned — and they did no reverie statistical pose logistic regression — that at 50 ng/ mL, there was zero mortality.

The federal government is recognized that vitamin D deficiency … is ubiquitous in rest home[ and minorities] … So, that we didn’t have a vitamin D etiquette nationally is criminal. Literally, it’s criminal.”

In the hospital treatment protocol, the FLCCC recommends using calcitriol, 0.5 micrograms on Day 1 and 0.25 mcg daily thereafter for six dates. Calcitriol is the active form of vitamin D commonly produced in your kidneys.

This is because merely taking regular oral vitamin D neglects in acute positions as it takes weeks to be metabolized to its active structure. Calcitriol is the active form, so it will start to work immediately. One can also take the vitamin D, though, as eventually adequate blood levels will be reached and the calcitriol can be discontinued.

Why Men Do Worse than Women in COVID

As mentioned earlier, the protocol also includes a number of nutraceuticals, such as quercetin and zinc. Another dope that inspections promising is fluvoxamine, an antidepressant. Kory says πŸ˜› TAGEND

“The studies continue to pan out, and even clinically, some of honourable colleagues who incorporated ivermectin with fluvoxamine construe much less treatment failings. I grade it as highly effective, but it doesn’t cure everybody. They examined an periodic treatment miscarry and they said it certainly disappeared once they use the combo.

For someone older or with more advanced disease, more comorbidities, obese cases, diabetics, I tend to throw the kitchen submerge at those tribes. I try to use as many elements in the protocol as I can. So there, I’ll lent fluvoxamine.

The game changer now is antiandrogens. We use spironolactone, which is a potassium-sparing diuretic, at doses above 100 mg a daytime. It has potent antiandrogen belongings, as well as dutasteride, a 5-alpha reductase inhibitor, which too inhibits testosterone.

Androgens seem to be a huge potential driver of this illness , not only in terms of driving viral replication, but also in potentially facilitating inflammation … The tests on that are really, truly potent … so, we have an antiandrogen aspect. I’ve been using that on some of my older or more advanced disease patients. I’ll add that on pretty quick.”

Residence Treatment Recommendations for COVID

While it can be difficult to find a doctor who is willing to actually treat COVID-1 9 with the FLCCC protocol( or any other for that matter ), many of those who are willing are fully used of telemedicine.

You can find a listing of doctors who can prescribe ivermectin and other necessary prescriptions on the FLCCC website. There, you can also find downloadable PDFs in several languages for prevention and early at-home treatment, the in-hospital protocol and long-term management guidance for long-haul COVID-1 9 illnes. Three other etiquettes that have great success are πŸ˜› TAGEND

The AAPS protocolTess Laurie’s World Council for Health protocolAmerica’s Frontline DoctorsDr. Peter McCullough

This is a load of information to review, peculiarly if you are fatigued and sick with COVID or have a family member struggling. So, I reviewed all the protocols and repute the FLCCC one is the easiest and most effective to follow. I’ve affixed it below.

However, I’ve reformed some of the dosages, and contributed a few more cares that they have yet to include, such as πŸ˜› TAGEND

Nebulize hydrogen peroxide 5 ml of 0.1% peroxide disbanded in 0.9% regular saline every hour or two. It’s best to use nebulizer that pushes into the wall, as these are more effective than battery operated ones.

Intravenous ozone administered by a trained ozone physician.

NAC 500 mg twice a day.

Make sure the sugar is fresh honey , not ordinary honey from the convenience store. Raw honey can be obtained online or at a health food store.

Fibrinolytic enzymes like lumbrokinase, serrapeptidase or nattokinase, two to four tablets, two to 3 times per day, on an evacuate stomach( 1 hour before or two hours after a meal ). This will help break down any microclots.

Decrease zinc dose from 100 mg to 50 mg primordial zinc, but exclusively for three days, then abridge to 15 mg primal zinc.

Increased quercetin from 250 mg to 500 mg.

Change vitamin C to liposomal C 1,000 to 2,000 mg four to six times per day.

FLCCC Alliance I-MASKplus Protocol Alpha

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