Dalelorenzo's GDI Blog
8Jun/210

Why Your Hormones Have Been Hijacked

Plastic is such a pervasive part of modern life that it’s hard to imagine a life without it. But in the magnificent arrangement of things, plastics are still a brand-new fabrication, and as noted by Pete Myers, Ph.D ., the chair, founder and chief scientist of Environmental Health Science, in the video above, there’s a lot we don’t know about plastics and health -- but then, there’s a lot that we do.

Particularly when it comes to the chemicals in plastics, much is known about the risks this represents to human health, including to future generations through intergenerational endocrine disruption. “It’s enough to give me enormou intermission, ” Myers says.

Endocrine disruptors, which are widespread in plastic produces, are similar in structure to natural sex hormones such as estrogen, thereby interfering with their regular gatherings -- and more. According to Myers, the future of humankind could ultimately be at risk: 1

“Your hormones have been hijacked. Your body's astonishing, finely gauged signal structure -- a plan that ascertains everything from your heavines to your fertility to your mood -- has been scrambled by loosely settled substances creators use in a myriad of ways including in consumer products.

These hijackers -- known to scientists as' endocrine-disrupting chemicals’ -- are threatening our life as a category. Driving this trouble are chemical companies focused only on inexpensive plastics and regulators unwilling to do anything about it.”

Male Fertility Is on the Decline, Could Reach Zero by 2045

Myers highlights the book “Count Down, ” written by Shanna Swan, a reproductive epidemiologist at Mount Sinai's Icahn School of Medicine. It’s based on a 2017 study she co-wrote, which felt sperm weighs has decreased by 59.3% from 1973 to 2011.2

The most significant declines were found in tests from mortals in The americas, Europe, Australia and New Zealand, where countless had sperm concentrations below 40 million/ ml, which is considered the cutoff point at which a boy will have trouble fertilizing an egg. Overall, men in these countries had a 52.4% decline in sperm concentration and a 59.3% decline in total seman counting( seman concentration proliferated by the total volume of an ejaculate ).

The book expands on what Swan describes as an impending birthrate crisis; together with the dropping sperm weighs, the changing nature of sex progress pose challenges to human existence and, according to Swan, “The current state of reproductive things can’t continue much longer without warning human survival.”3 In actuality, she is of the view that if current juttings continue, sperm tallies could contact zero in 2045.

Global fertility rates are also dropping, contacting 2.4 deliveries per female in 2018, down from 5.06 in 1964. Fertility paces in about 50% of countries worldwide are at 2.1, which is below person replacement tier, Legal guardians reported. 4

Human beings once convene three of the five criteria for what makes a categories endangered, according to Swan, and while there are numerous influences involved -- including contraception and costs of raising children -- biological intellects, such as declining sperm counts, increasing stillbirth charges and genital irregularities, are also driving down birth and fertility rates.

Endocrine-disrupting “everywhere chemicals” are a key culprit, she says: “Chemicals in environmental matters and undesirable life-style practices in our contemporary world are interrupting our hormonal offset, justification numerous grades of reproductive havoc.”5

Has the' Count Down’ to Infertility Begun?

“Count Down” creates some little-known procures into the spotlight, like the facts of the case that a significant part of the global population may not be able to reproduce without technological succor come 2050.6 And, the book indicates, beings today have about half the number of sperm compared to their grandfathers.

“I'm half the man my grandfather was, and my grandsons will be half the man I am. In some countries, half of all duets striving maternity expect medical intervention, ” Myers wrote. 7 There appears to be a synergy pas as well, which the book dubs “the 1% result, ” because sperm count, testosterone and fertility are falling, and testicular cancer and miscarriage are rising, all at about 1 % per year. 8P TAGEND

Environmental substances, especially endocrine-disrupting substances( EDCs ), are another common thread, linked to increasing difficulties in women’s fertility as well as men’s. “Studies are finding correlations between EDC exposure and an increase in failures and congenital disorder, and a decline in egg quality and quantity. EDCs can even change a child in utero if uncovered during pregnancy, ” Sustainable Pulse reported. 9

Chemical exposure during pregnancy has been found to affect both masculinization and long-term fertility in males. In the wildernes, fish, frogs and reptiles are also increasingly being born with both ovaries and testes. 10

Environmental Chemicals Causing Fertility Declines

A number of compounds are wreaking desolation with human birthrate. EDCs interfere with endogenous hormones, and it’s been found that some effects of exposure persist in future generations, even among males that weren’t instantly uncovered. 11

Research published in PLOS Genetics, for instance, found that exposing male mice to ethinyl estradiol, a synthetic fornication hormone found in birth control pills, motives developmental problems in the reproduction treatise, thereby lowering sperm weighs( people may be exposed to birth control lozenges through infected liquid and other sources ). The generational effects of EDCs were also divulged. Environmental Health News reported: 12

"They saw adverse impact starting in the first generation of mouse progenies where each contemporary was exposed for a brief period shortly after birth. The repercussions worsened in the second generation compared to the first, and by the third generation the scientists were discovering swine that could not produce sperm at all.

This latter condition was not seen in the first two generations disclosed. Items of the experimental solutions actually suggested that multiple generations of show may have increased male sense to the chemical."

Adding further reinforce that environmental compounds are involved in fertility rejects is investigate indicating similar rejects in seman character in dogs living in human households, with sperm motility diminishing by 30% over a 26 -year period. 13

In the canine study, health researchers connected specific environmental substances to sperm problems and recommended they could also be responsible for the seman tone refuses in humans -- a notion supported by a study published in Scientific Reports. 14

Researchers from the University of Nottingham employed seman samples from 11 men and nine bird-dogs from the same U.K. region. They exposed the seman to doses of two types of environmental substances, diethylhexyl phthalate( DEHP) and polychlorinated biphenyl 153( PCB1 53 ), currently found in the environment. The decision was reduced sperm motility and increased DNA fragmentation.

The investigates speculate dogs may act as a “sentinel” for lessens in male fertility and that manmade chemicals used extensively in residence and working conditions are the likely criminal. A previous study even spotcheck such compounds in hound sperm and some dog food. 15

Top Root of Endocrine Disruptors

The Environmental Working Group( EWG) worded the following entry 12 chemicals in their “dirty dozen” list of EDCs: 16

Bisphenol-A( BPA )

Dioxin

Atrazine

Phthalates

Perchlorate

Fire retardants

Lead

Mercury

Arsenic

Perfluorinated substances( PFCs)

Organophosphate pesticides

Glycol ethers

Such chemicals are pervasive, being found in everything from nutrient, drinking water and household goods to personal charge commodities, emptying produces , nonstick cookware and plastics. Others, like atrazine, are banned in the The european institutions but still widely used in the U.S.

Early research by Tyrone Hayes, Ph.D ., an integrative biologist at the University of California, Berkeley, hypothesized that atrazine turned on an enzyme( aromatase) that justification testosterone to be converted into estrogen. If you’re a male, this means that you won’t perform sperm, but you are able to form estrogen, even though you shouldn’t.

According to Hayes and collaborators in research published in Nature in 2002, exposure to water-borne atrazine contamination led to “gonadal abnormalities such as retarded development and hermaphroditism” in 10% to 92% of male wildernes leopard frogs. Hayes published another study in 2010 in Proceedings of the National Academy of Science( PNAS ), which had similar sees. 17

Phthalates, another class of compounds on the index, are linked to hormone changes and triggering “'death-inducing signaling’ in testicular cadres, stirring them die earlier than they are able to, ” EWG memorandum. 18 And this is just one of their toxic effects( they’ve also come under shoot for impairing brain development, increasing children’s risk of learning, attending and behavioral disorders1 9 ).

It’s important to remember that everything from antidepressants2 0 and dullnes to your dietary options and EMF exposure can affect your fertility. I’ve previously compiled some tips for increasing sperm count now.

As for reducing exposure to noxious phthalates and other EDCs that may “hijack your hormones” with disastrous consequences on birthrate and more, the following steps may help, but "youre seeing" more tips for forestalling EDCs now.

Avoid plastic containers and plastic wrap for meat and personal charge produces. Store food and sucks in glass receptacles instead.

Avoid plastic children's dolls. Use toys made of natural substances, such as wood and organic materials.

Read descriptions on your cosmetics and bypassed those containing phthalates.

Avoid concoctions labeled with "fragrance, ” including air fresheners, as this catch-all term may include phthalates commonly used to stabilize the scent and extend the life of the product.

Read labels looking for PVC-free makes, including children's lunch chests, backpacks and storage containers.

Do not microwave food in plastic containers or should be included in plastic wrap.

Frequently vacuum and dust offices with vinyl blinds, wallpaper, flooring and furniture that may contain phthalates as the chemical accumulates in dust and is easily ingested by children.

Ask your pharmacist if your prescription capsules are coated to control when they dissolve as the veneer may contain phthalates.

Eat mostly fresh, raw entire meat. Food packaging is often a source of phthalates.

Use glass baby bottles instead of plastic. Breastfeed alone for the first time, if it is possible to, to avoid plastic breasts and bottles altogether.

Remove your fruit and vegetables from plastic bags immediately after coming home from the convenience store and clean before collecting them; alternatively, use cloth baggages to brought before your produce.

Cash register acknowledgments are heat engraved and often contain BPA. Handle the receipt as little as possible and ask the store to be changed to BP-Afree receipts.

Use natural cleaning makes or start your own.

Replace feminine hygiene commodities with safer alternatives.

Avoid fabric softeners and dryer membranes; establish your own to reduce static cling.

Check your home's tap water for contaminants and filter the sea if necessary.

Teach your children not to suck from the garden-variety hose, as countless contain plasticizers such as phthalates.

Use reusable shopping bags for groceries.

Take your own non-plastic leftovers receptacle to eateries. Avoid disposable utensils and straws.

Bring your own mug for chocolate and fetching drinking water from home in glass water bottles instead of buying bottled water.

Consider switching to bamboo toothbrushes and grazing your teeth with coconut lubricant and baking soda to avoid plastic toothpaste tubes.

Read more: articles.mercola.com

1Apr/210

Study: 55 Formerly Unknown Chemicals Found in Pregnant Women

The phrase “better living through chemistry” is a variation on an advertising campaign used by the DuPont Chemical Company1 in the mid-1 930 s until the early 1980 s.

In 2014,2 "its become" the name of a “comedy” that represents the life of a husband bullied by "his fathers" and spouse, and his subsequent “rebirth” through chemical employment. Nonetheless, the Hollywood and public relations different versions of “better living through chemistry” are not the reality.

For instance, recent data from the University of California San Francisco revealed that 55 compounds previously not is located within humen were found in the bodies of pregnant women and their babies. 3

Chemical-laden plastic has become such a ubiquitous part of modern-day life that is hard to imagine a world without it. Yet, in the stately programme of things, it's a relatively new invention4 and there's still a good deal we don't know about how it affects human and environmental health.

The substances in plastic are intergenerational endocrine disruptors5 for which there is not enough evidence to demonstrate plastic is safe for current and future generations. These compounds have widespread use in plastic produces and are similar in nature to natural sex hormones, which makes them the designation of endocrine disruptors.

But the compounds in plastics are just one of the enormous number of chemicals being released into the environment through human use and disposal in waste products, including human garbage. For example, according to the Environmental Working Group, 6 every day women in America use an average of 12 personal charge makes, including cosmetics, that contain up to 168 different chemicals.

And those are just the substances the manufacturers have told the public is in those products. Many of these are applied to the skin, which accepts ingredients to be absorbed immediately into the bloodstream. This is only one of the ways chemicals are absorbed in the body.

For example, meat can acquaint chemicals in the body, either through its ingredients or through its package. The fast-food industry was valued at $ 647.7 billion in 2019 and is estimated to grow 4.6% by 2027, reaching $931.7 billion. 7 Yet, despite the fact that it has been identified as a significant source of hormone-disrupting compounds, the market continues to grow as consumer demand increases.

Scientists Find 42' Mystery Chemicals’ in Pregnant Women

In the boasted study, researchers8 felt 109 substances working high-resolution mass spectrometry on blood samples from pregnant women and their children. The study was done to develop a screening workflow for the identification and the priorities of chemical show in maternal and cord blood samples as a development for the future evaluation of health risks.

In a small sample of 30 women their babies’ cord serum samples, they found 55 previously unreported compounds in human blood. In addition to this, they too attained 42 “mystery chemicals” with generators and uses that were unidentified by the researchers. 9 The scientists expressed the view that the broad masses of the 55 combinations had “limited to no information about their informants or uses.”1 0

However, the source of the chemicals is believed to be from consumer products and other industrial informants, as written in a press release from the University of California. 11 Since they were found in both the pregnant both women and their newborn children, sign suggests the compounds are able to pass across the placenta.

Tracey Woodruff, Ph.D ., is a professor of obstetrics, gynecology and reproductive disciplines at the University of California San Francisco and major investigate on studies and research. She noted in the press release: 12

“These substances have probably been in people for some time, but our technology is now helping us to identify more of them. It is alarming that we maintain checking specific substances circulate from pregnant women to their children, which makes these compounds can be with us for generations. It’s unusually concerning that we are unable to identify the uses or sources of so many of these chemicals.”

Woodruff spoke to a writer from Live Science, 13 showing her concerns that exposure during pregnancy is dangerous since it's at a vulnerable duration of proliferation, potentially leading to lifelong ramifications. Two of the recently seen substances in the human body were polyfluoroalkyl or perfluoroalkyl chemicals( PFASs ), used in concoctions such as pizza caskets and nonstick cookware.

Ten were plasticizers, such as phthalates, but the majority of the newly identified chemicals the researchers had no information about. Another columnist, Dimitri Abrahamsson, told Live Science that the number of members of compounds detected should signal a sense of “alarm, ” continuing: 14

"We're being exposed to chemicals that we have very little information about. And these chemicals could potentially have harmful health effects that we don't know and can't predict.”

Phthalates and Plasticizers Pose Health Dangers

Data from the Norwegian Institute of Public Health discovered 90% of the person or persons measured from 2016 to 2017 had eight different plasticizers in their urine. 15 These colorless, odorless chemicals, arranged principally of phthalates, are used to change the elasticity of materials during the manufacturing process. 16

Although you can probably name shower curtains, takeout containers and storage bags as plastic commodities, did you know clothing, paper coffee cups, tea pockets and chewing gum are also made with plastic? 17 Because the chemicals are not tightly bound to the products, they can dissipate into the surrounding environment, including the food you munched and the water you suck.

While the National Toxicology Program1 8 imagines phthalates are “reasonably considered to be a human carcinogen, ” politics and regulations have allowed plastics to stay in many of the products you use today.

In addition to the passage of compounds from mom to child, ingestion of plastic corpuscles can start in infancy. Globally, the baby bottle industry was estimated at $ 2.6 billion in 2018, and the plastic segment been taken into consideration 44.1% of the overall share. 19 Researchers2 0 found that microplastics are liberated from plastic baby bottles into the contents, sometimes up to 16 million plastic molecules per liter.

In this study, investigates experimented simply the number of members of particles released by the bottle as they use sanctified irrigate and not standard drinking water. Since standard drinking water also contains microplastics, 21 this necessitates the number may have been significantly underestimated when the bottles are used at home.

Phthalates are potent hormone disruptors that can cause males in many genus to develop feminine characteristics. 22 By disrupting the endocrine system they can also increase the risk of testicular cancer, low-pitched seman tally and infertility, which investigates have found in animal species including whales, deer, otters and bears.

A peer-reviewed article published in the American Journal of Public Health2 3 used data from longitudinal birth cohort studies to show associations between revelation to phthalates in utero and attention deficit hyperactivity disorder, lower IQ, impaired social communication, poverty-stricken psychomotor development and untoward cognitive development.

EPA and FDA Responsible for Your Toxic Exposure

Woodruff and her team were able to tentatively identify some of the chemicals used in chemical libraries. However, proof is made by comparing them to the pure substances known as “analytical standards, ” provided by the manufacturer. Manufacturer do not always provision the tests. Woodruff continued her testimony in the press release from the University of California, saying: 24

“EPA must do a better job of asking the chemical industry to standardize its reporting of chemical compounds and uses. And they need to use their authority to ensure that we have adequate information to evaluate potential health ills and remove compounds from world markets that pose a risk.”

During the UCSF study, investigates received chemical make Solvay halted access to a chemical standard for one of their perfluorooctanoic battery-acid combinations they have used as a permutation for those that have been phased out. The investigates had been applying this chemical standard as a similarity, looking forward to the spirit and toxicity of the replacing substance. 25

It may seem strange that a regulated industry would have the option of withdrawing its compound composition, but as Sharyl Attkisson from Full Measure2 6 indicates that there is an investigative report, service industries is self-regulated. When the law was passed in 1938, it was missing a section that would have given the FDA the authority to impose sanctions.

Melanie Benesh of the Environmental Working Group told Attkisson that the FDA does not have jurisdiction to recall products or “to do a systematic look at their ingredients and what their long-term effects are.”

While the FDA has no teeth, the EPA is not using its regulatory sovereignty in many cases. According to their website, the EPA “gathers health, safety and exposure data; compels required testing; and controls human and environmental showings for several chemical substances and combines. EPA regulates the production and distribution of commercial-grade and industrial chemicals ... ”2 7

Yet, as I have covered in the past, the EPA has been litigated for its mercury policy, countenancing dental agencies to continue to discharge virtually 5.1 tons of mercury each year into publicly owned water treatment weeds, most of which are subsequently released into the environment. 28

The EPA has also been accused of colluding with Monsanto, which you can read more about in “Evidence EPA Colluded With Monsanto to Dismiss Cancer Concerns Grows Stronger.” They have blocked warning labels about glyphosate, and they promote the use of sewage sludge, which they dubbed “biosolids.”

This sludge is spread as fertilizer on U.S. agricultural lands, golf course, parklands and graveyards. As described in “BioSludged, ”2 9 biosolids can contain dioxins, medications, surfactants, hormones and heavy metals, as well as disease-causing pathogens.

The persistence of these toxins in the treated grunge means they may be absorbed by meat crops that end up on your plateful. Yet, high-profile PR business, some funded by the EPA, twisting biosolids as environmentally friendly and a way of recycling.

The EPA’s Environmental Dumping Ground

According to the World Wildlife Federation, 30 between 1930 and 2000, there was a 400 -fold increase in the production of man-made chemicals all over the world, emerge from 1 million to 400 million tons each year. These man-made compounds develop widespread environmental contamination during their manufacture, use and disposal.

Chemicals can advance massive lengths through the aura or liquid and have been found to contaminate nearly every environment and type of wildlife, including fledglings, alligators, polar stands and panthers. There has been a widespread decline of mink in the Great Lagoon, otters in Canada and other categories across North America and Western Europe. 31

Experts believe it is the environmental contamination of polychlorinated biphenyls( PCBs) and dioxins, which is supported by studies squandering laboratory mink. Perfluorooctane sulfonate( PFOS) is classified by the U.S. EPA as a cancer-causing agent. It has been found in the Mediterranean to the Baltic Sea.

In 1979, it was tested on apes and they all died within weeks. Scientists have found caimans, an alligator species native to South America, with sexuality changes caused by environmental impurity from bisphenol A. The chemical was also responsible for reproductive malformations in quail and chicken embryos.

Consider Your Daily Choices

It doesn't appear that the EPA or FDA has plans to go wide-ranging steps to warn the public about perilous environmental substances now or in the very near future. To the contrary, in some cases, they're working with the companies to remove warning labels that could have alerted consumers to their risks, such as the incident in California where the EPA stepped in to remove warning labels about glyphosate. 32

Despite scientific indication to the contrary, 33,34, 35 to date the EPA continues to insist that there is “No evidence that glyphosate cases cancer in humans.”3 6 Governmental regulatory agencies do not appear willing to go against large manufacturers in order to protect the health of their citizens.

Instead, it's up to you to vote with your billfold and keep an eye on the products and services that you use. For example, one highway to promote change in the cosmetic manufacture is to participate in tracking adverse events3 7 from any chemical or commodity you use.

Instead of buying the newest celebrity-endorsed personal maintenance commodity or cosmetic, consider making your own bath and handwashing makes without preservatives. Seek out safe produces that are free of potentially dangerous substances by using the Environmental Working Group’s Skin Deep Database. 38

The easiest way to steer clear of glyphosate is to buy locally and organically grown food from a trusted informant. For a inventory of ways to help reduce your revelation to endocrine-disrupting substances, consider “Why Your Hormones Have Been Hijacked.”

Read more: articles.mercola.com