Dalelorenzo's GDI Blog
1Apr/210

Study: 55 Formerly Unknown Chemicals Found in Pregnant Women

The phrase “better living through chemistry” is a variation on an advertising campaign used by the DuPont Chemical Company1 in the mid-1 930 s until the early 1980 s.

In 2014,2 "its become" the name of a “comedy” that represents the life of a husband bullied by "his fathers" and spouse, and his subsequent “rebirth” through chemical employment. Nonetheless, the Hollywood and public relations different versions of “better living through chemistry” are not the reality.

For instance, recent data from the University of California San Francisco revealed that 55 compounds previously not is located within humen were found in the bodies of pregnant women and their babies. 3

Chemical-laden plastic has become such a ubiquitous part of modern-day life that is hard to imagine a world without it. Yet, in the stately programme of things, it's a relatively new invention4 and there's still a good deal we don't know about how it affects human and environmental health.

The substances in plastic are intergenerational endocrine disruptors5 for which there is not enough evidence to demonstrate plastic is safe for current and future generations. These compounds have widespread use in plastic produces and are similar in nature to natural sex hormones, which makes them the designation of endocrine disruptors.

But the compounds in plastics are just one of the enormous number of chemicals being released into the environment through human use and disposal in waste products, including human garbage. For example, according to the Environmental Working Group, 6 every day women in America use an average of 12 personal charge makes, including cosmetics, that contain up to 168 different chemicals.

And those are just the substances the manufacturers have told the public is in those products. Many of these are applied to the skin, which accepts ingredients to be absorbed immediately into the bloodstream. This is only one of the ways chemicals are absorbed in the body.

For example, meat can acquaint chemicals in the body, either through its ingredients or through its package. The fast-food industry was valued at $ 647.7 billion in 2019 and is estimated to grow 4.6% by 2027, reaching $931.7 billion. 7 Yet, despite the fact that it has been identified as a significant source of hormone-disrupting compounds, the market continues to grow as consumer demand increases.

Scientists Find 42' Mystery Chemicals’ in Pregnant Women

In the boasted study, researchers8 felt 109 substances working high-resolution mass spectrometry on blood samples from pregnant women and their children. The study was done to develop a screening workflow for the identification and the priorities of chemical show in maternal and cord blood samples as a development for the future evaluation of health risks.

In a small sample of 30 women their babies’ cord serum samples, they found 55 previously unreported compounds in human blood. In addition to this, they too attained 42 “mystery chemicals” with generators and uses that were unidentified by the researchers. 9 The scientists expressed the view that the broad masses of the 55 combinations had “limited to no information about their informants or uses.”1 0

However, the source of the chemicals is believed to be from consumer products and other industrial informants, as written in a press release from the University of California. 11 Since they were found in both the pregnant both women and their newborn children, sign suggests the compounds are able to pass across the placenta.

Tracey Woodruff, Ph.D ., is a professor of obstetrics, gynecology and reproductive disciplines at the University of California San Francisco and major investigate on studies and research. She noted in the press release: 12

“These substances have probably been in people for some time, but our technology is now helping us to identify more of them. It is alarming that we maintain checking specific substances circulate from pregnant women to their children, which makes these compounds can be with us for generations. It’s unusually concerning that we are unable to identify the uses or sources of so many of these chemicals.”

Woodruff spoke to a writer from Live Science, 13 showing her concerns that exposure during pregnancy is dangerous since it's at a vulnerable duration of proliferation, potentially leading to lifelong ramifications. Two of the recently seen substances in the human body were polyfluoroalkyl or perfluoroalkyl chemicals( PFASs ), used in concoctions such as pizza caskets and nonstick cookware.

Ten were plasticizers, such as phthalates, but the majority of the newly identified chemicals the researchers had no information about. Another columnist, Dimitri Abrahamsson, told Live Science that the number of members of compounds detected should signal a sense of “alarm, ” continuing: 14

"We're being exposed to chemicals that we have very little information about. And these chemicals could potentially have harmful health effects that we don't know and can't predict.”

Phthalates and Plasticizers Pose Health Dangers

Data from the Norwegian Institute of Public Health discovered 90% of the person or persons measured from 2016 to 2017 had eight different plasticizers in their urine. 15 These colorless, odorless chemicals, arranged principally of phthalates, are used to change the elasticity of materials during the manufacturing process. 16

Although you can probably name shower curtains, takeout containers and storage bags as plastic commodities, did you know clothing, paper coffee cups, tea pockets and chewing gum are also made with plastic? 17 Because the chemicals are not tightly bound to the products, they can dissipate into the surrounding environment, including the food you munched and the water you suck.

While the National Toxicology Program1 8 imagines phthalates are “reasonably considered to be a human carcinogen, ” politics and regulations have allowed plastics to stay in many of the products you use today.

In addition to the passage of compounds from mom to child, ingestion of plastic corpuscles can start in infancy. Globally, the baby bottle industry was estimated at $ 2.6 billion in 2018, and the plastic segment been taken into consideration 44.1% of the overall share. 19 Researchers2 0 found that microplastics are liberated from plastic baby bottles into the contents, sometimes up to 16 million plastic molecules per liter.

In this study, investigates experimented simply the number of members of particles released by the bottle as they use sanctified irrigate and not standard drinking water. Since standard drinking water also contains microplastics, 21 this necessitates the number may have been significantly underestimated when the bottles are used at home.

Phthalates are potent hormone disruptors that can cause males in many genus to develop feminine characteristics. 22 By disrupting the endocrine system they can also increase the risk of testicular cancer, low-pitched seman tally and infertility, which investigates have found in animal species including whales, deer, otters and bears.

A peer-reviewed article published in the American Journal of Public Health2 3 used data from longitudinal birth cohort studies to show associations between revelation to phthalates in utero and attention deficit hyperactivity disorder, lower IQ, impaired social communication, poverty-stricken psychomotor development and untoward cognitive development.

EPA and FDA Responsible for Your Toxic Exposure

Woodruff and her team were able to tentatively identify some of the chemicals used in chemical libraries. However, proof is made by comparing them to the pure substances known as “analytical standards, ” provided by the manufacturer. Manufacturer do not always provision the tests. Woodruff continued her testimony in the press release from the University of California, saying: 24

“EPA must do a better job of asking the chemical industry to standardize its reporting of chemical compounds and uses. And they need to use their authority to ensure that we have adequate information to evaluate potential health ills and remove compounds from world markets that pose a risk.”

During the UCSF study, investigates received chemical make Solvay halted access to a chemical standard for one of their perfluorooctanoic battery-acid combinations they have used as a permutation for those that have been phased out. The investigates had been applying this chemical standard as a similarity, looking forward to the spirit and toxicity of the replacing substance. 25

It may seem strange that a regulated industry would have the option of withdrawing its compound composition, but as Sharyl Attkisson from Full Measure2 6 indicates that there is an investigative report, service industries is self-regulated. When the law was passed in 1938, it was missing a section that would have given the FDA the authority to impose sanctions.

Melanie Benesh of the Environmental Working Group told Attkisson that the FDA does not have jurisdiction to recall products or “to do a systematic look at their ingredients and what their long-term effects are.”

While the FDA has no teeth, the EPA is not using its regulatory sovereignty in many cases. According to their website, the EPA “gathers health, safety and exposure data; compels required testing; and controls human and environmental showings for several chemical substances and combines. EPA regulates the production and distribution of commercial-grade and industrial chemicals ... ”2 7

Yet, as I have covered in the past, the EPA has been litigated for its mercury policy, countenancing dental agencies to continue to discharge virtually 5.1 tons of mercury each year into publicly owned water treatment weeds, most of which are subsequently released into the environment. 28

The EPA has also been accused of colluding with Monsanto, which you can read more about in “Evidence EPA Colluded With Monsanto to Dismiss Cancer Concerns Grows Stronger.” They have blocked warning labels about glyphosate, and they promote the use of sewage sludge, which they dubbed “biosolids.”

This sludge is spread as fertilizer on U.S. agricultural lands, golf course, parklands and graveyards. As described in “BioSludged, ”2 9 biosolids can contain dioxins, medications, surfactants, hormones and heavy metals, as well as disease-causing pathogens.

The persistence of these toxins in the treated grunge means they may be absorbed by meat crops that end up on your plateful. Yet, high-profile PR business, some funded by the EPA, twisting biosolids as environmentally friendly and a way of recycling.

The EPA’s Environmental Dumping Ground

According to the World Wildlife Federation, 30 between 1930 and 2000, there was a 400 -fold increase in the production of man-made chemicals all over the world, emerge from 1 million to 400 million tons each year. These man-made compounds develop widespread environmental contamination during their manufacture, use and disposal.

Chemicals can advance massive lengths through the aura or liquid and have been found to contaminate nearly every environment and type of wildlife, including fledglings, alligators, polar stands and panthers. There has been a widespread decline of mink in the Great Lagoon, otters in Canada and other categories across North America and Western Europe. 31

Experts believe it is the environmental contamination of polychlorinated biphenyls( PCBs) and dioxins, which is supported by studies squandering laboratory mink. Perfluorooctane sulfonate( PFOS) is classified by the U.S. EPA as a cancer-causing agent. It has been found in the Mediterranean to the Baltic Sea.

In 1979, it was tested on apes and they all died within weeks. Scientists have found caimans, an alligator species native to South America, with sexuality changes caused by environmental impurity from bisphenol A. The chemical was also responsible for reproductive malformations in quail and chicken embryos.

Consider Your Daily Choices

It doesn't appear that the EPA or FDA has plans to go wide-ranging steps to warn the public about perilous environmental substances now or in the very near future. To the contrary, in some cases, they're working with the companies to remove warning labels that could have alerted consumers to their risks, such as the incident in California where the EPA stepped in to remove warning labels about glyphosate. 32

Despite scientific indication to the contrary, 33,34, 35 to date the EPA continues to insist that there is “No evidence that glyphosate cases cancer in humans.”3 6 Governmental regulatory agencies do not appear willing to go against large manufacturers in order to protect the health of their citizens.

Instead, it's up to you to vote with your billfold and keep an eye on the products and services that you use. For example, one highway to promote change in the cosmetic manufacture is to participate in tracking adverse events3 7 from any chemical or commodity you use.

Instead of buying the newest celebrity-endorsed personal maintenance commodity or cosmetic, consider making your own bath and handwashing makes without preservatives. Seek out safe produces that are free of potentially dangerous substances by using the Environmental Working Group’s Skin Deep Database. 38

The easiest way to steer clear of glyphosate is to buy locally and organically grown food from a trusted informant. For a inventory of ways to help reduce your revelation to endocrine-disrupting substances, consider “Why Your Hormones Have Been Hijacked.”

Read more: articles.mercola.com

26Mar/210

Phthalates Are Damaging Babies’ Brains

Ubiquitous exposure to phthalates, found in everything from menu carton to personal care makes, is putting children’s brain development at risk, according to Project TENDR( Targeting Environmental Neuro-Development Risks ), a collaboration of scientists, health professionals and advocates for children and the environment. 1

The group worded in 2015 due to concerns that lethal environmental substances were playing a role in neurodevelopmental disorders including autism, notice inadequacies, hyperactivity, academic disability and learning disorders.

Recently, they’ve sharpened in on phthalates, meeting that enough exhibit exists to call for immediate action to protect children’s brains from exposure to this harmful class of compounds. 2

Several Behavioral Disorders Linked to Phthalates

Phthalates are high-production magnitude chemicals used frequently as plasticizers in polyvinyl chloride( PVC) and other plastics.

An reckoned 8.4 million metric tons of plasticizers, including phthalates, are used worldwide each year, 3 with phthalate yield is tantamount to about 4.9 million metric tons annually. 4 The Norwegian Institute of Public Health found that 90% of those experimented from 2016 to 2017 had eight different plasticizers in their urine. 5

In a peer-reviewed article published in the American Journal of Public Health, members of Project TENDR came to the conclusion that exposure to ortho-phthalates can impair brain development, increasing children’s risk of learning, courtesy and behavioral disorders.

They cite data from longitudinal birth cohort studies that substantiate associations between showing to phthalates in utero and the following health conditions: 6

Attention-deficit hyperactivity disorder( ADHD )

Other behavioral problems

Adverse cognitive development

Lower IQ

Poorer psychomotor development

Impaired social communication

According to the report, more than 30 published studies from 11 different countries have valued prenatal phthalate exposure with the children being followed for alterations in neonatal behaviour, cognitive growth, ministerial serve, social behavior and more.

“The most consistent motif across multiple studies is associations with demeanors often associated with ADHD( including hyperactivity, invasion/ disregard and feeling reactivity ), lacks in executive perform or ADHD clinical diagnosis, ” the researchers memo. 7

In one example, children born to moms that were in the highest quintile of urinary phthalate heights( specific, DEHP metabolites) during the second trimester of pregnancy were nearly three times more likely to be diagnosed with ADHD compared to children born to mothers in the lowest quintile. 8P TAGEND

Prenatal exposure to phthalates, especially metabolites of DBP and DEHP, has been linked to a range of added problem behaviors such as an increased likelihood of delinquent demeanors and most aggressive actions, 9 along with reductions in child perceptual reasoning, lowered IQ by seven places, feeling and poorer working remembrance. 10

Prenatal Exposures Through Puberty Particularly Problematic

There are various confidential windows of exposure to phthalates, including prenatally and postnatally into adolescence and potentially adulthood. The ongoing development of the intelligence, including the prefrontal cortex, hippocampus and cerebellum, during these periods make it especially vulnerable to revelations to phthalates toxicities.

The mechanisms behind phthalates’ harms are varied, but the substances are known to disrupt organization and perform of the hypothalamic-pituitary-gonadal axis, the system responsible for the management of stress and involved in the regulation of immune function and metabolic homeostasis. They may also inhibit fetal testosterone product and may also have antiestrogenic influences, 11 which could have repercussions for psyche plasticity. 12

“The hippocampus and, consequently, particular aspects of neural plasticity, cognitive flexible, anxiety-like behavior, learning and memory, are thought to be particularly vulnerable to phthalates, ” the team noted, 13 adding that phthalates may also cause harm by disrupting thyroid hormone pathways and adjusting lipid metabolism and ion homeostasis, including calcium signaling and peroxisome proliferator-activated receptors activating. They memo: 14

“Given the widespread exposures to phthalates, including among women and children, and the limitations of existing US regulations , nothing of which focus on pregnant women, health-protective regulatory actions are required to eliminate these potentially harmful exposures.”

How Are You To be subject to Phthalates?

While the U.S. employed restrictions on the use of eight phthalates in children’s playthings and other child care pieces, this is being legally challenged by the National Association of Creator, the American Chemistry Council and other industry radicals. 15

Further federal regulation of the chemicals remains sloppy and, in fact, the U.S. Food and Drug Administration approved the use of 28 phthalates for utilize as artificial additive in food contact commodities, such as cellophane, newspaper and paperboard, coating negotiators and binders.

Environmental and public health make-ups deferred applications inviting the FDA to eliminate its approval of the 28 phthalates as food additive but the FDA did not meet the statutory deadline for final decision. 16

As a arise, nutrition continues to be a significant route of exposure to phthalates, since the substances can leach into food is not simply from food packaging commonly used by fast food and take-out diners but likewise from plastic paraphernalium used in food production, such as commercial dairy, conveyor belts and food preparation mitts. 17

Another common roadway of show is from building furnishes, including vinyl flooring and wall shields, which tolerate phthalates to migrate into household dust and indoor breeze. They’re likewise widely used in personal care produces and cosmetics, including tack polish, balm, liniment and fuzz products.

“Overall, girls have higher show to phthalates found in personal care makes than servicemen, ” the report indicated, which is especially problematic since “[ p] hthalates are readily transferred from father to fetus during pregnancy.”1 8P TAGEND

All Phthalates Should Be Regulated, Eliminated

Because beings are exposed to multiple phthalates simultaneously, the report called for regulation of the chemicals as a class and policy reforms to eliminate the substances from commodities that lead to exposure in pregnant women, women around reproduction age, infants and children.

“We're exposed to multiple phthalates, and that combination can come within a single commodity, but also across multiple commodities that people are to be subject to in a date, " lead author Stephanie Engel told CNN. "The reality is that we need to think of phthalates as a class because that's how people are exposed to them.”1 9

Reviewing the chemicals as a class would also prevent manufacturers from simply swapping one phthalate with another, same to what passed with bisphenol-A and bisphenol-S. Linda Birnbaum, former director of the National Institute for Environmental Health Science and the National Toxicology Program, told CNN: 20

"This is the whole history of these chemicals, whether you call it 'whack a mole' or 'chemical conveyor belt' or 'unfortunate substitution.' We move from one chemical that we have concerns about to another one which we just haven't studied hitherto, which often turns out to be just as problematic.

We can't continue to test these things one at a time. I could make an debate that if one chemical can be substituted for another without modifying the process, then why would you think the biology would be different? "

While industry groups have pushed back due to the “costs” associated with removing the chemicals, some retailers and makes have already taken voluntary action to replace them. Home Depot feed plan to curb phthalates in vinyl flooring and wall-to-wall carpeting, for example, and Apple removed the class of chemicals from nearly all of its concoctions. 21

Microplastic Pollution Is Another Human Health Crisis

In a perspective article be made available in the journal Science, Dick Vethaak from Vrije Universiteit Amsterdam and Juliette Legler from Utrecht University in the Netherlands suggest that ubiquitous exposure to microplastics, including plastic corpuscles smaller than 5 millimeters and nanosized plastics smaller than 1 um, represent another significant risk to human health. 22,23

Exposure comes via both breath and ingestion and is the consequence of the endless explosion of plastic commodities such as car tires, robing, paint membranes and more, which comes in shapes such as arenas, fragments and fibers. The plastics contain mixtures of chemicals, including supplements and other environmental contaminants.

“[ A] thriving person of testify hints widespread showing to microplastics from various foods, drinking water and air, ” the researchers mentioned, said microplastics may cause physical, chemical and microbiological toxicity in humans, with the toxic effects playing cumulatively.

In addition, chemical toxicity could also occur since microplastics may act as “vectors to transfer exogenous hazardous substances, proteins and toxins present in or on the specks into the body.”2 4 They pointed out a little-known and understudied potential hazard as well -- the presence of an eco- or biocornoa, who the hell is substances on the surface area of the plastic particle that could be used to is in conflict with normal molecule uptake: 25

“Before crossing the epithelial impediments in the lung and intestine, microplastics are trapped in the mucus blanket embracing the cells, whereas ingested molecules have to pass through acidic living conditions in the stomach and intestinal lumen.

The role of the changing composition of the eco- or biocorona acquired by microparticles, from the outside to the inside of the body, across tissue barricades, and the underlying mechanisms in mediating uptake and toxicity are was all right and deserve more study.”

In a study at University of Newcastle, Australia, researchers quantified what microplastic exposure may means for humen, exposing a shocking locate that the average person could be eating about 5 grams of plastic per week -- about the amount found in one credit card. 26

While environmental groups have called for national targets for plastic reduction, recycling and administration, along with an international treaty to stop plastic pollution in the oceans and seas, don’t underestimate the impact one person -- you -- can have by making simple tweaks to your daily life.

By avoiding the use of single-use plastics like straws, utensils, pouches and bottles, and seeking to purchase makes that are not made from or are available in plastic, you can make a dent in the amount of plastic litter and contamination being produced.

How to Reduce Your Phthalate Exposure

You can take steps to reduce your show to phthalates and other plasticizers by making small changes in your everyday routine. This includes 😛 TAGEND

Avoid plastic receptacles and plastic wrap for food and personal attend produces. Store food and sucks in glass containers instead.

Avoid plastic children's playthings. Use toys make use of natural elements, such as wood and organic materials.

Read labels on your cosmetics and avoid those containing phthalates.

Avoid commodities labeled with “fragrance, ” including breath fresheners, as this catch-all term may include phthalates commonly used to stabilize the scent and extend the life of the product.

Read names looking for PVC-free concoctions, including children's lunch caskets, knapsacks and storage containers.

Do not microwave meat in plastic containers or covered in plastic wrap.

Frequently vacuum and dust apartments with vinyl blinds, wallpaper, flooring and furniture that may contain phthalates, as the chemical rallies in dust and is easily assimilated by children.

Ask your pharmacist if your drug pills are coated to control when they dissolve as the coating may contain phthalates.

Eat mostly fresh, fresh entire meat. Food packaging is often a source of phthalates.

Use glass baby bottles instead of plastic. Breastfeed exclusively for the first time, if you can, to avoid plastic teats and bottles altogether.

Remove your fresh fruit and veggies from plastic bags immediately after coming home from the food market and rinse before accumulating them; instead, use cloth bags to bring home your produce.

Cash register acknowledgments are heat printed and often contain BPA. Handle the receipt as little as is practicable and ask the storage to switch to BP-Afree receipts.

Use natural clean makes or obligate your own.

Replace feminine hygiene produces with safer alternatives.

Avoid fabric softeners and dryer sheets; prepare your own to reduce static cling.

Check your home's tap water for contaminants and filter the irrigate if necessary.

Teach your children not to imbibe from the plot hose, as countless hoses contain plasticizers such as phthalates.

Use reusable shopping bags for groceries.

Take your own non-plastic leftovers container to restaurants. Avoid expendable utensils and straws.

Bring your own mug for chocolate and imparting clean drinking water from home in glass water bottles instead of buying bottled water.

Consider switching to bamboo toothbrushes and brushing your teeth with coconut lubricant and baking soda to avoid plastic toothpaste tubes.

Read more: articles.mercola.com